Methyl chloroformate → HCID 12805007, compound

Participants

Reaction Steps

6.0 g (29.5 millimoles) of 6-(p-aminophenyl)-4,5-dihydro-dihydro-5-methyl-3(2H)-pyridazinone and 3.3 g (34.9 millimoles) of methyl chloroformate in 100 ml of absolute toluene are kept for 6 hours at 80° C. The product is filtered off at 10° C., washed first with toluene and then with water, and recrystallized from dimethylformamide/water. 3.1 g (40% of theory) of 4,5-dihydro-6-(p-methoxycarbonylaminophenyl)-5-methyl-3(2H)-pyridazinone are obtained as colorless crystals, of melting point 228°-229° C.

Provenance & Evidence