HuagongsheHuagongshe Chemistry Print Report · For research reference only
Vanillin → HCID 15583557, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Vanillin | HCID 1183 | — |
| Reactant | 5-Fluorouracil | HCID 3385 | — |
| Reactant | HCID 20480607 | HCID 20480607 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15583557 | HCID 15583557 | 34.6% |
Reaction Steps
To the solution of 2-(3-methoxy-4-acetoxyphenyl)-1,3-dioxolan (22 g) prepared from 3-methoxy-4-hydroxybenzaldehyde as in Example 12 in dichloromethane (50 ml) bis(trimethylsilyl)-5-fluorouracil prepared from 5-fluorouracil (10 g) was added followed by treating as in Example 10 to give 9.8 g of crystalline 1-[α-(2-hydroxyethoxy)-3-methoxy-4-acetoxybenzyl]-5-fluorouracil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04415573 |
| Source dataset | uspto-grants-1983_11 |
| ORD ID | ord-c8666eba6629456aaa92572059cab4b7 |
| Source note | uspto-grants-1983_11 |