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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1649129Generated: October 29, 2026

Thionyl Chloride → 6,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chloride

https://huagongshe.com/reaction/1649129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant6,7-Dihydroxychromon-3-carboxylic acidHCID 12200776—
Product6,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chlorideHCID 12765757—

Reaction Steps

6,7-Dihydroxychromone-3-carboxylic acid (888 mg) and 25 ml of thionyl chloride were refluxed for one hour. Then, the thionyl chloride was removed by distillation, and after benzene was added, further distillation was conducted. Dichloromethane was added into the residue for solidification, whereby the desired product (719 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04415567
Source datasetuspto-grants-1983_11
ORD IDord-4345520310e84411b701f7e628c1ad9f
Source noteuspto-grants-1983_11