4-Methoxybenzylamine → HCID 13236307, compound

Participants

Reaction Steps

A mixture of 2.32 g of 6-morpholino-3,4-dihydrocarbostyril and 14.7 g of 4-methoxybenzylamine was placed in a sealed tube and heated at 170° to 200° C. for 5 hours. Excessive 4-methoxybenzylamine was distilled off under reduced pressure and the residue was isolated and purified through silica gel column chromatography followed by recrystallization from ethanol to give 0.35 g of 6-[4-(4-methoxybenzyl)-1-piperazinyl]-3,4-dihydrocarbostyril, m.p. 196°-198° C., colorless needles.

Provenance & Evidence