m-Chloroperbenzoic acid → HCID 54410203, compound

Participants

Reaction Steps

A solution of 85% pure meta-chloroperbenzoic acid (0.05 g) in methylene chloride (1 cc) is added all at once to a solution, cooled to -10° C., of product (13d) (0.2 g) in methylene chloride (5 cc). After 30 minutes at -10° C., the reaction mixture is diluted with ethyl acetate (20 cc) and washed with a saturated solution of sodium bicarbonate (2×10 cc) and a saturated solution of sodium chloride (2×10 cc). After the organic phase has been dried over sodium sulphate and concentrated to dryness under reduced pressure (30 mm Hg; 4 kPa) at 30° C., a crude product (13a) (0.15 g) is obtained in the form of a hard orange foam.

Provenance & Evidence