Hydrazine → HCID 178441179, compound

HRID 1649318Notes

Reaction equation

HRID 1649318 reaction equation
[C:1]([C:5]([CH2:7][C:8]#[N:9])=O)([CH3:4])([CH3:3])[CH3:2].[NH2:10][NH2:11]>C(O)C>[CH3:2][C:1]([C:5]1[CH:7]=[C:8]([NH2:9])[NH:11][N:10]=1)([CH3:4])[CH3:3]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 108871Pentanenitrile, 4,4-dimethyl-3-oxo-

Product 1

HCID 178441179HCID 178441179, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The ketone thus formed was dissolved in 150 ml of ethanol containing 32 g of hydrazine. The reaction mixture was heated at reflux for twelve hours, and then cooled to room temperature. Removal of the solvent by evaporation under reduced pressure provided a solid residue, which when triturated with 250 ml of petroleum ether, filtered and air dried, was identified as 12.5 g of 3-tert.-butyl-5-amino-1H-pyrazole.

Workup

  1. temperatureThe reaction mixture was heated
  2. temperatureat reflux for twelve hours
  3. customRemoval of the solvent
  4. customby evaporation under reduced pressure
  5. customprovided a solid residue, which when
  6. customtriturated with 250 ml of petroleum ether
  7. filtrationfiltered
  8. customair dried

Sources & evidence

ORD record
ord-4deb294b3ee14f519bc7f086ecabaac4
Source dataset
uspto-grants-1983_11
Patent number
US04416683

Reaction notes

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