HCID 86739131, compound → HCID 86739132, compound

Participants

Reaction Steps

To a solution of N-(4-phenyl-4-hydroxy-2-trans-butenyl)-N,N-diethylamine (44.04 g) in chloroform (1000 ml), manganese dioxide (350 g) was added portionwise with stirring at 15° to 20° C. for 10 minutes, and stirring was continued for 3 hours under ice-cooling. After filtration of inorganic materials, the filtrate was evaporated to afford N-(4-phenyl-4-oxo-2-trans-butenyl)-N,N-diethylamine, which formed its hydrobromide with a solution of hydrogen bromide (16.3 g) in anhydrous ether (200 ml), m.p., 92°-94° C.

Provenance & Evidence