Succinate → Raloxifene Bismethyl Ether

HRID 1649600Notes

Reaction equation

HRID 1649600 reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:9]([C:10](=[O:26])[C:11]3[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][N:20]4[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]4)=[CH:13][CH:12]=3)=[C:8]([C:27]3[CH:32]=[CH:31][C:30]([O:33][CH:34](C)C)=[CH:29][CH:28]=3)[S:7][C:6]=2[CH:37]=1.[C:38]([O-])(=O)CCC([O-])=O>>[CH3:38][O:1][C:2]1[CH:3]=[CH:4][C:5]2[C:9]([C:10](=[O:26])[C:11]3[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][N:20]4[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]4)=[CH:13][CH:12]=3)=[C:8]([C:27]3[CH:32]=[CH:31][C:30]([O:33][CH3:34])=[CH:29][CH:28]=3)[S:7][C:6]=2[CH:37]=1

Participants

3

Reactant 2

HCID 160419SuccinateHCID 20479006HCID 20479006, compound

Product 1

HCID 10767755Raloxifene Bismethyl Ether

Procedure

6-hydroxy-2-(4-isopropoxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene, succinate

Sources & evidence

ORD record
ord-da32040544b7434286f2a09080da241f
Source dataset
uspto-grants-1983_11
Patent number
US04418068

Reaction notes

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