HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 6-[1-Hydroxy-2-(imidazol-1-yl)ethyl]-3,4-dihydrocarbostyril
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 6-(Imidazol-1-ylacetyl)-3,4-dihydrocarbostyril | HCID 14207262 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-[1-Hydroxy-2-(imidazol-1-yl)ethyl]-3,4-dihydrocarbostyril | HCID 14373292 | — |
Reaction Steps
A solution of 3.0 g of 6-(imidazol-1-ylacetyl)-3,4-dihydrocarbostyril (the preparation of which is given in Example 3) in 120 ml of methanol was reacted with 1.2 g of sodium borohydride in the same manner as shown in Preparation 2, and the product similarly isolated to give 6-[1-hydroxy-2-(imidazol-1-yl)ethyl]-3,4-dihydrocarbostyril, m.p. 182°-184°
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04921862 |
| Source dataset | uspto-grants-1990_05 |
| ORD ID | ord-e2a97beaa9eb44abbb9e21febed68157 |
| Source note | uspto-grants-1990_05 |