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Hydrochloric Acid → 6-[3-(Imidazol-1-yl)propyl]-3,4-dihydrocarbostyril hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 6-[3-(Imidazol-1-yl)propyl]-3,4-dihydrocarbostyril acetate | HCID 19854608 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 6-[3-(Imidazol-1-yl)propyl]-3,4-dihydrocarbostyril hydrochloride | HCID 19854738 | — |
反応手順
6-[3-(imidazol-1-yl)propyl]-3,4-dihydrocarbostyril acetate (1.0 g) is dissolved in 50 ml of methanol and a stoichiometric amount of a solution of hydrochloric acid in methanol is added. The solvent is removed under vacuum and the residue recrystallised from a mixture of methanol and ethyl acetate to yield 6-[3-(imidazol-1-yl)propyl]-3,4-dihydrocarbostyril hydrochloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04921862 |
| 出典データセット | uspto-grants-1990_05 |
| ORD ID | ord-564a2cee6c4440098fec428c435787de |
| 出典メモ | uspto-grants-1990_05 |