HuagongsheHuagongshe Chemistry Print Report · For research reference only
benzyl 2(S)-morpholinocarbonyloxy-3-phenylpropionate → O-(N-Morpholinocarbonyl)-3-phenyllactic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | benzyl 2(S)-morpholinocarbonyloxy-3-phenylpropionate | HCID 18638974 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | O-(N-Morpholinocarbonyl)-3-phenyllactic acid | HCID 195075 | 97% |
Reaction Steps
A solution of benzyl 2(S)-morpholinocarbonyloxy-3-phenylpropionate (300 mg) in methanol (20 ml) was hydrogenated over 10% palladium on carbon (30 mg) at 3 atmospheric pressure of hydrogen for 1 hour. The solution was filtered and concentrated in vacuo to give 2(S)-morpholinocarbonyloxy-3-phenylpropionic acid (220 mg) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04921855 |
| Source dataset | uspto-grants-1990_05 |
| ORD ID | ord-798b88f056cb4b968e173002ea1d9edb |
| Source note | uspto-grants-1990_05 |