HCID 67926739, compound → HCID 67926747, compound

HRID 1650157Notes

Reaction equation

HRID 1650157 reaction equation
[CH3:1][CH:2]1[C:7]([C:8]2[CH:24]=[CH:23][C:11]3[N:12]=[C:13]([C:15]4[O:16][C:17]([N+:20]([O-])=O)=[CH:18][CH:19]=4)[NH:14][C:10]=3[CH:9]=2)=[N:6][NH:5][C:4](=[O:25])[CH2:3]1>CO.[Pd]>[CH3:1][CH:2]1[C:7]([C:8]2[CH:24]=[CH:23][C:11]3[N:12]=[C:13]([C:15]4[O:16][C:17]([NH2:20])=[CH:18][CH:19]=4)[NH:14][C:10]=3[CH:9]=2)=[N:6][NH:5][C:4](=[O:25])[CH2:3]1

Participants

4

Reactant 1

HCID 67926739HCID 67926739, compound

Product 1

HCID 67926747HCID 67926747, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of 1 g of 5-methyl-6-[2-(5-nitro-2-furyl)-5-benzimidazolyl]-4,5-dihydropyridazin-3-one in 30 ml of methanol is hydrogenated to completion on 0.2 g of 5% Pd-C at 20° and under 1 bar. The mixture is filtered, the filtrate is evaporated, and 5-methyl-6-[2-(5-amino-2-furyl)-5-benzimidazolyl]-4,5-dihydropyridazin-3-one is obtained.

Workup

  1. filtrationThe mixture is filtered
  2. customthe filtrate is evaporated

Sources & evidence

ORD record
ord-fa8e62f48a7d48b7aecaad058d971ad5
Source dataset
uspto-grants-1990_05
Patent number
US04923869

Reaction notes

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