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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1650348Generated: October 30, 2026

(5-Methylpyrimidin-2-yl)methanol → 5-Methylpyrimidine-2-carbaldehyde

https://huagongshe.com/reaction/1650348

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Methylpyrimidin-2-yl)methanolHCID 23043337—
CatalystHCID 178418406HCID 178418406—
SolventChloroformHCID 6212—
Product5-Methylpyrimidine-2-carbaldehydeHCID 23043336—

Reaction Steps

5-Methylpyrimidine-2-carboxaldehyde was prepared from 2-hydroxymethyl-5-methylpyrimidine by oxidation with excess manganese dioxide in boiling chloroform. The product was obtained as colourless crystals and was characterized by proton nuclear magnetic resonance spectroscopy. Proton nuclear magnetic resonance spectrum (CDCl3 ; δ in ppm): 2.44 (3H,s); 8.80 (2H,s); 10.06 (1H,s).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04923989
Source datasetuspto-grants-1990_05
ORD IDord-84eae02268f744098681b12933a9b494
Source noteuspto-grants-1990_05