Sodium Hydroxide → HCID 20060070, compound

HRID 1650657Notes

Reaction equation

HRID 1650657 reaction equation
[CH3:1][CH:2]([CH2:17][CH3:18])[CH2:3][N:4]1[C:12]2[N:11]=[C:10]([CH2:13][CH3:14])[NH:9][C:8]=2[C:7](=O)[NH:6][C:5]1=[O:16].P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:20].[OH-].[Na+]>N1C=CC=CC=1>[CH3:1][CH:2]([CH2:17][CH3:18])[CH2:3][N:4]1[C:12]2[N:11]=[C:10]([CH2:13][CH3:14])[NH:9][C:8]=2[C:7](=[S:20])[NH:6][C:5]1=[O:16]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 14817Phosphorus sulfide (P2S5)HCID 20060066HCID 20060066, compound

Product 1

HCID 20060070HCID 20060070, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Conditions

Temperature
10 °C

Procedure

3-(2-Methylbutyl)-8-ethylxanthine (13.33 gm) and phosphorus pentasulphide (14.23 gm) were refluxed in pyridine (190 ml) at a bath temperature of 140° C. After 4.5 hr, the brown solution was cooled to 10° C. and 2N sodium hydroxide {70 ml) was added. The pyridine was removed in vacuo from the suspension.

Workup

  1. customThe pyridine was removed in vacuo from the suspension

Sources & evidence

ORD record
ord-d40be34bb63044cfbab741c07ce71569
Source dataset
uspto-grants-1990_05
Patent number
US04925847

Reaction notes

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