Hydrochloric Acid → HCID 53794998, compound

Participants

Reaction Steps

2-(2-(3-Cyanophenyl)ethenyl)benzthiazole (3.00 g, 11.5 mmol) was dissolved in 50 ml of ethanol. After 10 ml of 30% aqueous potassium hydroxide solution was added, the resulting mixture was heated under reflux for 19 hours. The reaction mixture was cooled, neutralized with 5% hydrochloric acid, extracted with ethyl acetate, and dried. The solvent was then distilled out to produce a crude product. This crude crystal was washed with ether to afford the indicated compound (2.60 g) with a yield of 81%.

Provenance & Evidence