Potassium cyanate → HCID 178441880, compound

HRID 1650766Notes

Reaction equation

HRID 1650766 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[C:3]=1[NH:10][N:11]=[C:12](Cl)[C:13]([CH3:16])([CH3:15])[CH3:14].[O-:18][C:19]#[N:20].[K+]>C(O)C.O>[OH:18][C:19]1[N:10]([C:3]2[C:2]([Cl:1])=[CH:7][C:6]([Cl:8])=[CH:5][C:4]=2[Cl:9])[N:11]=[C:12]([C:13]([CH3:16])([CH3:15])[CH3:14])[N:20]=1

Participants

5

Reactant 2

HCID 11378442Potassium cyanateHCID 85820415HCID 85820415, compound

Product 1

HCID 178441880HCID 178441880, compoundYield 95.3%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

6.3 g (0.02 mol) of 2,2-dimethylpropionyl chloride 2,4,6-trichlorophenylhydrazone was dissolved in 50 ml of ethanol. Then, a solution of 3.2 g (0.04 mol) of potassium cyanate in 30 ml of water, was dropwise added thereto under stirring at room temperature. After completion of the dropwise addition, stirring was continued at the same temperature for further 0.5 hour. The precipitated crystals were collected by filtration and washed with n-hexane to obtain 6.1 g (yield: 95.3%) of 5-hydroxy-3-(tert-butyl)-1-(2,4,6-trichlorophenyl)-1H-1,2,4-triazole as white powder having a melting point of from 272° to 274° C.

Workup

  1. additionAfter completion of the dropwise addition
  2. stirringstirring
  3. filtrationThe precipitated crystals were collected by filtration
  4. washwashed with n-hexane

Sources & evidence

ORD record
ord-f0422ed8fd934b41bfb953a616f625b6
Source dataset
uspto-grants-1990_05
Patent number
US04925864

Reaction notes

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