3,5,5-Trimethyl-2-pyrazoline → 1-(2,6-Dichlorophenylsulphonylcarbamoyl)-3,5,5-trimethyl-2-pyrazoline

HRID 1650989Notes

Reaction equation

HRID 1650989 reaction equation
[CH3:1][C:2]1[CH2:6][C:5]([CH3:8])([CH3:7])[NH:4][N:3]=1.[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[C:11]=1[S:17]([N:20]=[C:21]=[O:22])(=[O:19])=[O:18]>O.C1(C)C=CC=CC=1>[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[C:11]=1[S:17]([NH:20][C:21]([N:4]1[C:5]([CH3:8])([CH3:7])[CH2:6][C:2]([CH3:1])=[N:3]1)=[O:22])(=[O:18])=[O:19]

Participants

5

Reactant 2

HCID 2314643,5,5-Trimethyl-2-pyrazolineHCID 128751892,6-Dichlorobenzenesulfonyl isocyanate

Product 1

HCID 230508981-(2,6-Dichlorophenylsulphonylcarbamoyl)-3,5,5-trimethyl-2-pyrazoline

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 1140TolueneSolvent

Procedure

11.2 g of the 3,5,5-trimethyl-2-pyrazoline obtained according to example I(b) are added dropwise while stirring, cooling in cold water and under a nitrogen blanket to a solution of 25.2 g of the 2,6-dichlorobenzenesulphonylisocyanate obtained according to example I(a) in 200 ml of dry toluene. After stirring at room temperature for two hours, the precipitate is sucked off and washed successively with dry toluene and petroleum ether (40-60). The desired 1-(2,6-dichlorophenylsulphonylcarbamoyl)-3,5,5-trimethyl-2-pyrazoline is obtained in a yield of 20.07 g; melting-point 270° C. (decomposition).

Workup

  1. additionare added dropwise
  2. customobtained
  3. stirringAfter stirring at room temperature for two hours
  4. washwashed successively with dry toluene and petroleum ether (40-60)

Sources & evidence

ORD record
ord-cf3b4d36ab914790bb87113a3ce05a18
Source dataset
uspto-grants-1990_05
Patent number
US04927452

Reaction notes

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