L-Phenylalanine → 3-Cyclohexyl-L-alanine

Participants

Reaction Steps

2 g of L-phenylalanine was dissolved in 30 ml of a 50% of acetic acid, and hydrogenated by using 200 mg of platinum as catalyst under elevated pressure (hydrogen pressure: 50 kg/cm2) for 2 hours at a temperature from 40° to 70° C. The catalyst was filtered off and the solvent was distilled off under reduced pressured to obtain 2.2 g of L-cyclohexylalanine as a colorless needle crystal.

Provenance & Evidence