Sodium Hydroxide → HCID 15034333, compound

HRID 1651120Notes

Reaction equation

HRID 1651120 reaction equation
Cl.[CH2:2]([NH:9][CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[OH-].[Na+]>ClCCl>[CH2:2]([NH:9][CH2:10][CH2:11][O:12][C:13]1[CH:14]=[CH:15][C:16]([OH:19])=[CH:17][CH:18]=1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22154105HCID 22154105, compound

Product 1

HCID 15034333HCID 15034333, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

N-Benzyl-2-(p-hydroxyphenoxy)ethylamine hydrochloride (3.5 g) was shaken with 1M sodium hydroxide solution (20 ml) and dichloromethane (20 ml). The organic layer was separated and washed with water (10 ml), dried (MgSO4) and the solvent evaporated to give N-benzyl-2-(p-hydroxyphenoxy)ethylamine as an oil.

Workup

  1. customThe organic layer was separated
  2. washwashed with water (10 ml)
  3. dry with materialdried (MgSO4)
  4. customthe solvent evaporated

Sources & evidence

ORD record
ord-babd5f64f13f4413a1d51c1e40fdb045
Source dataset
uspto-grants-1990_05
Patent number
US04927836

Reaction notes

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