反应详情

10-Bromo-1,8-dihydroxy-9-anthrone (100 mg) was dissolved in dichloromethane (7 ml) and 2-mercaptoethanol (0.03 ml) was added. The solution was stirred at room temperature for 7 hours, during which time the light brown solution became pale green. Removal of the solvent and recrystallisation of the residue from a hexane/chloroform mixture (5:1) gave 10-(2-hydroxyethylthio)-1,8-dihydroxy-9-anthrone (89 mg, 90%) as pale yellow needles, melting point 146°-147° C. (Found: C 63.1, H 4.75, S 10.7; C16H14O4S requires C 63.55, H 4.7, S 10.6%).

1. customRemoval of the solvent and recrystallisation of the residue from a hexane/chloroform mixture (5:1)