1-Phenethylamine → 1-Phenethylamine

HRID 1651149Notes

Reaction equation

HRID 1651149 reaction equation
[CH:1]([S:14]([CH2:16][C:17]([OH:19])=[O:18])=[O:15])([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:20][CH:21]([NH2:28])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH:1]([S:14]([CH2:16][C:17]([O-:19])=[O:18])=[O:15])([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1.[CH3:20][CH:21]([NH2:28])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

4

Reactant 2

HCID 74081-PhenethylamineHCID 3085267Modafinil acid

Product 2

HCID 74081-PhenethylamineHCID 19020205(-)-Benzhydrylsulfinylacetate

Procedure

(1°) reacting (±)-benzhydrylsulfinylacetic acid with (-)-α-methylbenzylamine to give the (-)-benzhydrylsulfinylacetate of (-)-α-methylbenzylamine (the reaction advantageously being carried out in the presence of a small excess of amine relative to the stoichiometric conditions, and more particularly with a molar ratio amine/acid of between 1.02/1 and 1/15/1 and preferably of between 1.05/1 and 1.10/1),

Workup

  1. custom(1°)

Sources & evidence

ORD record
ord-187ce941a60f4537a97bcfb9b8680851
Source dataset
uspto-grants-1990_05
Patent number
US04927855

Reaction notes

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