HCID 10714229, compound → HCID 14500300, compound
Reaction equation
FC1C=CC(C2C(C3C=CC=CC=3)SC(C(C)C)C=2C(OCC)=O)=CC=1.[CH:27]([CH:30]1[C:34]([C:35]([O:37][CH2:38][CH3:39])=[O:36])=[C:33]([C:40]2[CH:45]=[CH:44][C:43]([F:46])=[CH:42][CH:41]=2)[CH:32]([C:47]2[CH:52]=[CH:51][C:50]([Cl:53])=[CH:49][CH:48]=2)[S:31]1)([CH3:29])[CH3:28]>>[CH:27]([C:30]1[S:31][C:32]([C:47]2[CH:52]=[CH:51][C:50]([Cl:53])=[CH:49][CH:48]=2)=[C:33]([C:40]2[CH:45]=[CH:44][C:43]([F:46])=[CH:42][CH:41]=2)[C:34]=1[C:35]([O:37][CH2:38][CH3:39])=[O:36])([CH3:28])[CH3:29]Participants
3
Procedure
Repeating the procedure described in Step 6 of Prep. 3, above, but using in place of the 4-(4-fluorophenyl)-2,5-dihydro 2-isopropyl-5-phenyl-3-thiophenecarboxylic acid, ethyl ester product thereof, an approximately equivalent amount of the refined product of Step 7 of this preparation, above, there is accordingly obtained the title product of this preparation.
Workup
- customabove, there is accordingly obtained
Sources & evidence
- ORD record
- ord-11d1c0fadc7641caa439aaf3dd9d64fe
- Source dataset
- uspto-grants-1990_05
- Patent number
- US04927851
Reaction notes
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