Trifluoroacetic acid → HCID 15166624, compound

Participants

Reaction Steps

A cold (0° C.) solution of 2.62 g of the product of Example 7 in 20 ml of dry anisole and 25 ml of dichloromethane was treated with 20 ml of trifluoroacetic acid. After evaporation the residue was chromatographed as described in Example 7, giving 950 mg of the desired product. 'H NMR (300 MHz, CDCl3): δ 2.57 (s, 3H); 3.70 (AB quartet, 2H, 4-CH2); 3.87 (s, 2H); 4.17 (AB quartet, 2H, CH2S--); 4.97 (d, 1H, J=4.8 Hz, 6-H); 5.76 (dd, 1H, J=9.24 Hz, 4.8 Hz, 7-H); [6.98 (m, 2H) and 7.24 (m, 1H)(thienyl)].

Provenance & Evidence