Triphenylphosphine → (7-Carboxyheptyl)triphenylphosphonium bromide

Participants

Reaction Steps

Triphenylphosphine (26.3 g) and 8-bromooctanoic acid (21.3 g) were reacted as in Example 82. The crude salt was crystallized from a mixture of ethanol (100 mL), chloroform (200 mL) and ether (500 mL) to give 41 g of (7-carboxyheptyl) triphenylphosphonium bromide, mp 121°-123° C. Anal. Calculated for C26H30BrO2P: C, 64.33; H, 6.23; Br, 16.46. Found: C, 63.97; H, 6.23; Br, 16.07.

Provenance & Evidence