Hydrochloric Acid → HCID 14742795, compound

Participants

Reaction Steps

A solution of (E)-3-(1-butyl-6-methoxy-2-naphthalenyl)-2-propenoic acid methyl ester (1.7 g) in methanol (10 mL) was treated with 2N sodium hydroxide (4.5 mL) and the mixture was stirred at reflux for 1 hour. The warm reaction mixture was acidified by the addition of 1N hydrochloric acid (9.2 mL). After the mixture cooled, the resulting solid was filtered off to provide 1.6 g of (E)-3-(1-butyl-6-methoxy-2-naphthalenyl)-2-propenoic acid. Crystallization of a portion from methanol gave the analytical specimen, mp 163°-164° C. Anal. Calcd for C18H20O3 : C, 76.03; H, 7.09 Found: C, 76.31; H, 7.32

Provenance & Evidence