Sodium Hydroxide → HCID 14742763, compound

Participants

Reaction Steps

As in Example 112, 1-butyl-7-methoxy-2-naphthalenecarboxylic acid ethyl ester (5.4 g) in methanol (40 mL) was reacted with 2N sodium hydroxide solution (20 mL) at reflux for 2 hours to give, after the normal work up, 4.9 g of crude acid. Crystallization of the material from diethyl ether-hexane furnished 4.22 g of 1-butyl-7-methoxy-2-naphthalenecarboxylic acid, mp 123°-125° C. Anal. Calcd for C16H18O3 : C, 74.39; H, 7.02 Found: C, 74.27; H, 6.93

Provenance & Evidence