反应详情

As in Example 113, (E)-3-(1-butyl-4-methoxy-2-naphthalenyl)-2-propenoic acid (3.7 g) was reacted with 4-nitrophenol (1.99 g) in dichloromethane (40 mL) in the presence of 1,3-dicyclohexylcarbodiimide (2.7 g). The crude reaction product was crystallized from 2-propanol to give 4.63 g of (E)-3-(1-butyl-4-methoxy-2-naphthalenyl)-2-propenoic acid 4-nitrophenyl ester, mp 121.5°-122.5° C. Anal. Calcd for C24H23NO5 : C, 71.10; H, 5.72; N, 3.45 Found: C, 70.93; H, 5.77; N, 3.52

1. customThe crude reaction product
2. customwas crystallized from 2-propanol