Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → HCID 14742790, compound

Participants

Reaction Steps

As in Example 111, 6-methoxy-3-pentyl-1H-2-indenecarboxaldehyde (8.5 g) and (carbomethoxymethylene)triphenylphosphorane (18.8 g) in dichloromethane (75 mL) was stirred at room temperature for 42 hours. The crude reaction product from the normal work up was purified by HPLC (diethyl ether-hexane; 1:3) to provide 6.4 g of (E)-3-(6-methoxy-3-pentyl-1H-inden-2-yl)-2-propenoic acid methyl ester as an oil.

Provenance & Evidence