反应详情

As in Example 113, (E)-3-(6-methoxy-3-pentylbenzofuran-2-yl)-2-propenoic acid (3.35 g) was reacted with 4-nitrophenol (1.8 g) in dichloromethane (35 mL) in the presence of 1,3-dicyclohexylcarbodiimide (2.42 g). The crude product was crystallized from 2-propanol to afford 4.1 g of (E)-3-(6-methoxy-3-pentylbenzofuran-2-yl)-2-propenoic acid 4-nitrophenyl ester, mp 120°-121.5° C. Anal. Calcd for C23H23NO6 : C, 67.47; H, 5.66; N, 3.42 Found: C, 67.29; H, 5.89; N, 3.43

1. customThe crude product was crystallized from 2-propanol