Methanethiol → HCID 14698107, compound

HRID 1651291Notes

Reaction equation

HRID 1651291 reaction equation
[CH3:1][SH:2].F[C:4]1[CH:18]=[CH:17][C:7]([C:8]([C:10]2[S:14][C:13](=[O:15])[NH:12][C:11]=2[CH3:16])=[O:9])=[CH:6][CH:5]=1>C(O)C>[CH3:16][C:11]1[NH:12][C:13](=[O:15])[S:14][C:10]=1[C:8](=[O:9])[C:7]1[CH:17]=[CH:18][C:4]([S:2][CH3:1])=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 878MethanethiolHCID 141522585-(4-Fluorobenzoyl)-4-methyl-1,3-thiazol-2(3H)-one

Product 1

HCID 14698107HCID 14698107, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Gaseous methylmercaptan is added to a solution of 5(4-fluorobenzoyl)-4-methyl-2(3H)-thiazolone (4.7 g) in ethanol (200 ml) to saturation. The mixture is heated at 120° C. in a sealed stainless steel container for 16 hours. After cooling to ambient temperature, the mixture is evaporated to dryness. The residue is recrystallized twice from ethanol to give the title compound.

Workup

  1. customthe mixture is evaporated to dryness
  2. customThe residue is recrystallized twice from ethanol

Sources & evidence

ORD record
ord-0e04c0338bd647e384822d6c14c11336
Source dataset
uspto-grants-1990_05
Patent number
US04927939

Reaction notes

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