Dicyclohexylamine → HCID 54115622, compound

Participants

Reaction Conditions

Reaction Steps

2.0 g (5 mmoles) of 4-[3-(1-adamantyl)-4-methoxy benzamido]benzoic acid are dissolved in 60 ml of THF. 1.1 g (6 mmoles of dicyclohexylamine are slowly added. A white precipitate is immediately formed. The reaction mixture is then cooled to 0° C. and 0.7 g (6 mmoles) of thionyl chloride is slowly added. The reaction mixture is stirred for 3 hours at ambient temperature. The solid that forms is filtered and then the filtrate is evaporated. The resulting residue is used, as is, in the following synthesis.

Provenance & Evidence