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HRID1651441

反应详情

EQUATION

反应方程式

HRID 1651441 的结构方程式

REACTANTS

反应物

1
结构：CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1N=C(c2ccccc2)S[C@H]1C(=O)OCc1ccccc1
HCID13773252

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1N=C(c2ccccc2)S[C@H]1C(=O)O
HCID13773254

未命名化合物

收率 36.7%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A solution of the product from step (c) (0.26g) in ethanol (20ml) was treated with 10% palladium on charcoal (0.lg) and stirred in a pressure vessel under hydrogen at 3 atmospheres at room temperature for 3 days. The catalyst was filtered off and the filtrate evaporated. The residue was triturated with ether to give the title product (0.08g) as a white solid, m.p. 180.5°-182°.

WORKUP

后处理

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate evaporated
  3. customThe residue was triturated with ether