HCID 14032380, compound → HCID 13773274, compound

Participants

Reaction Steps

The S,S,S benzyl ester from step (e) (1.8g) in ethanol (500ml) was hydrogenated over 10% Pd on charcoal (1.8g) at atmospheric pressure and room temperature for 5 hours. The catalyst was removed by filtration and the filtrate was evaporated to dryness. The residue was triturated with a 1:1 mixture of ether/petroleum ether 60°-80° to give the required acid as a white solid (1.3g). mp 183°-5°.

Provenance & Evidence