Acetic Acid → HCID 13773295, compound

Participants

Reaction Steps

1M Potassium hydroxide solution in methanol (5.83 ml) was added to a solution of the product of step (b) (0.87 g) in methanol (10 ml) and water (5 ml). The mixture was stirred under an atmosphere of nitrogen for 2 hours. Acetic acid was added and the solvent evaporated under reduced pressure. The mixture was purified by flash chromatography using 1% acetic acid/ethyl acetate as eluent to yield the title compound (0.24 g) as a white solid. mp 95°-97°.

Provenance & Evidence