Sulfuric Acid → HCID 15029584, compound

HRID 1651474Notes

Reaction equation

HRID 1651474 reaction equation
S(=O)(=O)(O)O.[C:6]([C:10]1[CH:11]=[CH:12][C:13]([O:20][CH3:21])=[C:14]([S:16]([Cl:19])(=[O:18])=[O:17])[CH:15]=1)([CH3:9])([CH3:8])[CH3:7].[N+:22]([O-])([O-:24])=[O:23].[K+]>ClCCl>[C:6]([C:10]1[CH:11]=[C:12]([N+:22]([O-:24])=[O:23])[C:13]([O:20][CH3:21])=[C:14]([S:16]([Cl:19])(=[O:18])=[O:17])[CH:15]=1)([CH3:9])([CH3:7])[CH3:8]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 24434Potassium NitrateHCID 132102315-tert-Butyl-2-methoxybenzene-1-sulfonyl chloride

Product 1

HCID 15029584HCID 15029584, compoundYield 86.3%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Concentrated sulphuric acid (13 ml) was added dropwise to a cooled mixture of 5-t-butyl 2-methoxyphenylsulfonyl chloride (9.0 g) and potassium nitrate (6.90 g) in dichloromethane (100 ml). The reaction mixture was then stirred for 16 hours at ambient temperature. The mixture was then poured onto ice-cold water (200 ml) and the organic layer was separated and dried over sodium sulphate. Removal of solvent gave the title compound as a pale yellow solid (9.1 g).

Workup

  1. additionThe mixture was then poured onto ice-cold water (200 ml)
  2. customthe organic layer was separated
  3. dry with materialdried over sodium sulphate
  4. customRemoval of solvent

Sources & evidence

ORD record
ord-d7e78fead2ca4996a220a39f17d1bb01
Source dataset
uspto-grants-1990_05
Patent number
US04929269

Reaction notes

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