HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Meridia
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sibutramine Hydrochloride | HCID 64764 | — |
| Product | Meridia | HCID 64765 | — |
Reaction Steps
A sample (48.2 g) of N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride was suspended and stirred with water (145 ml) for 24 hours at 25° C. The solid was collected by filtration and dried by suction at ambient temperature to give N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride monohydrate (m.p. 191°-195.5° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04929629 |
| Source dataset | uspto-grants-1990_05 |
| ORD ID | ord-7224928f44d143f7a44a592cd578a666 |
| Source note | uspto-grants-1990_05 |