HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylbenzylidenemalonic acid → 2-[(2-methylphenyl)methyl]propanedioic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylbenzylidenemalonic acid | HCID 10058800 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-[(2-methylphenyl)methyl]propanedioic Acid | HCID 2737546 | — |
Reaction Steps
Hydrogenate the acid of Step 1 (24.3 g) in EtOAc (600 ml) and EtOH (100 ml) at 60 psi with 5% Pd/C (1.0 g). After 2 hr., filter and concentrate to obtain the title compound as a beige solid, m.p. 132°-5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04929641 |
| Source dataset | uspto-grants-1990_05 |
| ORD ID | ord-8493594692ab4cebad87ac581f5d85ed |
| Source note | uspto-grants-1990_05 |