関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 1,1,1-Trichloro-2,2,2-trifluoroethane | HCID 9635 | — |
| 反応物 | 2,6-Dichloro-4-nitrobenzaldehyde | HCID 21838835 | — |
| 反応物 | HCID 178506323 | HCID 178506323 | — |
| 触媒 | Zinc | HCID 23994 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 2,2-Dichloro-3,3,3-trifluoro-1-(2,6-dichloro-4-nitrophenyl)-1-propanol | HCID 14848519 | — |
反応手順
3 g of 2,6-dichloro-4-nitro benzaldehyde were reacted, in 20 ml of anhydrous DMF under a nitrogen atmosphere, with CF3CCl2ZnCl prepared from 5 g of CF3CCl3 and 2.2 g of Zn in 10 ml of THF at 60° C. for 1 hour. The mixture was heated at 50° C. for 2 hours and at the end of the reaction it was poured into acidulated water and extracted repeatedly with ethyl ether.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04929772 |
|---|
| 出典データセット | uspto-grants-1990_05 |
|---|
| ORD ID | ord-fc35abf11ea146ab81193325dcbc2db0 |
|---|
| 出典メモ | uspto-grants-1990_05 |
|---|
