Trifluoroacetic acid → 1-Propyne, 3-(1-ethoxyethoxy)-

Participants

Reaction Steps

A solution of 20 g (0.36 mol) of 2-propyn-1-ol 1n 637 ml (6.66 mol) of ethyl vinyl ether was treated at 0° under argon with 1.27 ml (16.7 mmol) of trifluoroacetic acid and subsequently stirred at room temperature for 65 hours. 1.3 g of sodium carbonate were added, the react ion mixture was stirred at room temperature for a further 30 minutes and concentrated on a rotary evaporator. Distillation of the residue under reduced pressure Yielded 1-(1-ethoxyethoxy)-2-propyne of boiling point 55°/30 mmHg. MS: 127 (M-H) m/e.

Provenance & Evidence