HCID 23050473, compound → HCID 23050519, compound

Participants

Reaction Steps

A solution of 11.6 g (49 mmol) of methyl 4-hydroxy-4-[4-(methylthio)phenyl]-2-butynoate in 300 ml of methylene chloride was added dropwise at 0° to a suspension of 124 g (1.42 mol) of manganese dioxide in 300 ml of methylene chloride. The reaction mixture was stirred at 0° for 2 hours filtered over magnesium sulphate and concentrated. Crystallization of the residue from ether/hexane yielded methyl 3-[4-(methylthio)benzoyl]propiolate of melting point 74°-76°.

Provenance & Evidence