HCID 53903064, compound → HCID 17804063, compound

Participants

Reaction Steps

A solution of 10.7 g (39 mmol) of 3-methyl-2-butenyl 4-hydroxy-4-(4-methoxyphenyl)-2-butynoate in 150 ml of methylene chloride was added dropwise at 0° to a suspension of 101.7 g (1.17 mol) of manganese dioxide in 200 ml of methylene chloride. The reaction mixture was stirred at 0° for 1 hour, filtered over magnesium sulphate and concentrated. The residue was purified by flash chromatography on 700 g of silica gel (elution agent methylene chloride/ether 4:1). There was obtained 3-methyl-2-butenyl 3-(4-methoxybenzoyl)propiolate as a yellow oil.

Provenance & Evidence