Propargyl alcohol → HCID 11469074, compound

Participants

Reaction Steps

A solution of 29.6 ml (0.5 mol) of 2-propyn-1-ol in 500 ml of tetrahydrofuran was treated at -78° under argon with 67.3 g (0.6 mol) of potassium tert.-butylate. The mixture was stirred at -78° for 4 hours. 69.4 ml (0.6 mol) of 3,3-dimethylallyl bromide were then added and the mixture was stirred at -78° for a further 3 hours and at at room temperature for 20 hours. The reaction mixture was poured on to ice/water and extracted twice with ether. The combined organic phases were dried over magnesium sulphate and concentrated. There was obtained 1-[(3-methyl-2-butenyl)oxy]-2-propyne as a yellow oil which was processed without purification.

Provenance & Evidence