HCID 23050497, compound → HCID 23050503, compound

Participants

Reaction Steps

A solution of 34.2 g (125 mmol) of 1-hydroxy-4-[(3-methyl-2-butenyl)oxy)-1-(3,4-(methylenedioxy)phenyl]-2-butyne in 350 ml of methylene chloride was added dropwise at 0° to a suspension of 163 g (1.87 mol) of manganese dioxide in 500 ml of methylene chloride. The reaction mixture was stirred at 0° for 2 hours, filtered over magnesium sulphate and concentrated. The crude product was recrystallized from ether/hexane at -50°. There was obtained 4-[(3-methyl-2-butenyl)oxy]-1-[3,4-(methylenedioxy)phenyl]-2-butyn-1-one as pale yellow crystals which melt at room temperature.

Provenance & Evidence