Sodium Sulfate → HCID 23050477, compound

Participants

Reaction Steps

A solution of 53 g (155 mmol) of 4-methoxybenzyl 4-hydroxy-4-(3,4-methylenedioxyphenyl)-2-butynoate in 400 ml of methylene chloride was added dropwise at 0° to a suspension of 338 g (3.9 mol) of manganese dioxide in 800 ml of methylene chloride The reaction mixture was stirred at 0° for 1 hour, treated with 4 spatula tips of sodium sulphate, suction filtered over Dicalit and concentrated. Crystallization of the residue from ether yielded 4-methoxybenzyl 3-[3,4-(methylenedioxy)benzoyl]propiolate of melting point 113°-114°.

Provenance & Evidence