Thionyl Chloride → HCID 23050584, compound

HRID 1651858Notes

Reaction equation

HRID 1651858 reaction equation
[C:1]([NH:4][CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[C:10]([CH:14](O)[CH3:15])[CH:11]=2)[CH2:6]1)(=[O:3])[CH3:2].S(Cl)([Cl:19])=O>C(Cl)Cl>[C:1]([NH:4][CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[C:10]([CH:14]([Cl:19])[CH3:15])[CH:11]=2)[CH2:6]1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 23050553HCID 23050553, compound

Product 1

HCID 23050584HCID 23050584, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

25 g (0.11 mol) of 1-(2-acetamido-indan-5-yl)-1-ethanol are suspended in 280 ml of methylene chloride, and 15 g (0.12 mol) of thionyl chloride are added. A clear solution is formed. After 1 hour, this solution is neutralised by washing with a saturated solution of sodium bicarbonate. The desired reaction product is obtained after drying and evaporating.

Workup

  1. customA clear solution is formed
  2. washby washing with a saturated solution of sodium bicarbonate
  3. customThe desired reaction product
  4. customis obtained
  5. customafter drying
  6. customevaporating

Sources & evidence

ORD record
ord-3bf489313a514d5e88ca7201d43c6a47
Source dataset
uspto-grants-1990_05
Patent number
US04929754

Reaction notes

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