Sodium Hydroxide → 3-Methyl-4-(2-benzenesulphonamido-indan-5-yl)-4-oxobutyric acid

HRID 1651866Notes

Reaction equation

[CH3:1][CH:2]([C:8]([C:10]1[CH:11]=[C:12]2[C:16](=[CH:17][CH:18]=1)[CH2:15][CH:14]([NH:19][S:20]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)(=[O:22])=[O:21])[CH2:13]2)=[O:9])[CH2:3][C:4]([O:6]C)=[O:5].[OH-].[Na+]>>[CH3:1][CH:2]([C:8]([C:10]1[CH:11]=[C:12]2[C:16](=[CH:17][CH:18]=1)[CH2:15][CH:14]([NH:19][S:20]([C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1)(=[O:22])=[O:21])[CH2:13]2)=[O:9])[CH2:3][C:4]([OH:6])=[O:5]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 54122458HCID 54122458, compound

Product 1

HCID 140715173-Methyl-4-(2-benzenesulphonamido-indan-5-yl)-4-oxobutyric acid

Procedure

Prepared analogously to Example 2 from methyl 3-methyl-4-(2-benzenesulphonamido-indan-5-yl)-4-oxobutyrate by hydrolysis with sodium hydroxide.

Sources & evidence

ORD record: ord-568d46e91e5545678e78cbe4b288f2d1
Source dataset: uspto-grants-1990_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04929754

Reaction notes

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