Methyl iodide → HCID 20080675, compound

HRID 1653748Notes

Reaction equation

HRID 1653748 reaction equation
[OH:1][C:2]1([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH2:16][C:17]3[CH:26]=[CH:25][C:24]4[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=4)[CH:18]=3)[CH:10]=2)[CH2:8][CH2:7][CH2:6][O:5][CH2:4][CH2:3]1.[CH3:27]I>>[CH3:27][O:1][C:2]1([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH2:16][C:17]3[CH:26]=[CH:25][C:24]4[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=4)[CH:18]=3)[CH:10]=2)[CH2:8][CH2:7][CH2:6][O:5][CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 20080612HCID 20080612, compound

Product 1

HCID 20080675HCID 20080675, compoundYield 36%

Procedure

Using the procedure described in Example 1, 4-hydroxy-4-[3-(naphth-2-ylmethoxy)phenyl]oxepane was reacted with methyl iodide to give 4-methoxy-4-[3-(naphth-2-ylmethoxy)phenyl]oxepane (36%), m.p. 69°-70° C.

Sources & evidence

ORD record
ord-340740e8f22e40e18dbb54cd980ff455
Source dataset
uspto-grants-1995_04
Patent number
US05403859

Reaction notes

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