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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1653935Generated: October 30, 2026

(3-(Trifluoromethyl)phenyl)hydrazine → Sophorose

https://huagongshe.com/reaction/1653935

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-(Trifluoromethyl)phenyl)hydrazineHCID 98650—
Reactant(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 107526—
ReactantSodium AcetateHCID 517045—
ReactantD-glucose 3-(trifluoromethyl)phenyl hydrazoneHCID 86748606—
SolventWaterHCID 962—
ProductSophoroseHCID 92797—

Reaction Conditions

Temperature90 °C

Reaction Steps

To this oligosaccharide (10 μmol), sodium acetate (30 μmol) in a small vial (Pierce reacti-vial, 0.2 mL capacity, with Tuf-bond Teflon-silicone cap seals) was added 150 μL water. 3-(trifluoromethyl)phenylhydrazine (40 μmol, Aldrich) was added, the sample sealed under nitrogen, and heated to 90° C. for 48 hours. The oligosaccharide was converted (>98%) to D-glucose and D-glucose 3-(trifluoromethyl)phenyl hydrazone, in a 1:2 ratio.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05403927
Source datasetuspto-grants-1995_04
ORD IDord-497474b42c1c45b88ea6d1649eb81a59
Source noteuspto-grants-1995_04