HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 3-Carbamoyl-4-chloro-5-difluoromethoxy-1-methylpyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 5-(difluoromethoxy)-1-methyl-1H-pyrazole-3-carboxamide | HCID 53731990 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-Carbamoyl-4-chloro-5-difluoromethoxy-1-methylpyrazole | HCID 22912804 | — |
Reaction Steps
23,6 g (0.12 mole) 3-Carbamoyl-5-difluoromethoxy-1-methylpyrazole in 720 ml acetonitrile was treated with 16.7 g (0.12 mole) sulfuryl chloride and the mixture stirred for 10 minutes at room temperature. It was then concentrated and recrystallised from diisopropyl ether/ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05405829 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-1d40f4b59a2d43c0bbebe72f3186fd20 |
| Source note | uspto-grants-1995_04 |