Cyclopropane carboxylic acid chloride triethylamine → HCID 178418424, compound

HRID 1654Notes

Reaction equation

HRID 1654 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[CH:10]=[CH:9][C:8]([C@H:11]2[CH2:16][CH2:15][C@H:14]([OH:17])[CH2:13][CH2:12]2)=[CH:7][CH:6]=1)[CH3:3].[CH:18]1([C:21](Cl)=[O:22])[CH2:20][CH2:19]1.C(N(CC)CC)C>>[CH:18]1([C:21]([O:17][C@H:14]2[CH2:15][CH2:16][C@H:11]([C:8]3[CH:9]=[CH:10][C:5]([CH2:4][N:2]([CH3:1])[CH3:3])=[CH:6][CH:7]=3)[CH2:12][CH2:13]2)=[O:22])[CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 131720554Cyclopropane carboxylic acid chloride triethylamineHCID 178418401HCID 178418401, compound

Product 1

HCID 178418424HCID 178418424, compound

Procedure

from trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol and cyclopropane carboxylic acid chloride/triethylamine. Colourless wax.

Sources & evidence

ORD record
ord-7f6c0cb8ddf545bda5b486eb8435608e
Source dataset
uspto-grants-1998_03
Patent number
US05726205

Reaction notes

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